Embark your ship and settle into your stateroom. Chile’s modern capital of Santiago is one of the largest cities in the Americas. Its impressive neoclassical, neo-Gothic, art deco and other architecture spans several centuries. Santiago’s gateway, Valparaíso, is often compared to San Francisco for its many cerros, or hills. The city prospered as a major port until the opening of the Panama Canal rendered it unnecessary. Quaint Victorian-era architecture recalling its 19th-century affluence and steeply sloped barrios are linked by ascensores, or funiculars, and winding byways. From Los Cerros, the views are spectacular.